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American Journal of Clinical Nutrition, Vol 1, 44-51, Copyright © 1952 by The American Society for Clinical Nutrition, Inc.
1 From the Nutritional Research Laboratory, St. Luke's Hospital, New York
The data presented here support the view that in protein-depleted states a diet poor in one essential amino acid may be more deleterious than one poor in proteins. Evidence has also been presented which supports the concept that certain amino acid deficiencies in man can be identified by changes in amino acid levels in the urine or blood. The development of chromatographic procedures has greatly simplified this approach to the study of nutritional states in health and disease. In the near future we may therefore expect considerable advances in our knowledge of the aberrations of amino acid metabolism in various diseases; and from these advances there may develop a rational system of specific amino acid therapy.
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