AJCN Cancer Health Disparities Conference
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by FAILEY, R. B.
Right arrow Articles by MCCONAHAY, T. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by FAILEY, R. B., JR.
Right arrow Articles by MCCONAHAY, T. P.
Agricola
Right arrow Articles by FAILEY, R. B.
Right arrow Articles by MCCONAHAY, T. P.

American Journal of Clinical Nutrition, Vol 10, 158-162, Copyright © 1962 by The American Society for Clinical Nutrition, Inc.

The Effect of Para-Aminobenzoic Acid on the Serum Cholesterol Level in Man

ROBERT B. FAILEY JR. M.D.1, RICHARD H. CHILDRESS M.D.1, and THOMAS P. MCCONAHAY 1

1 From the Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana

Serum cholesterol levels in thirteen male subjects were determined during periods of medication with para-aminobenzoic acid at a dosage of 8 gm. daily. The average control value of 240.3 mg./100 ml. fell to 212.6 mg./100 ml. during the period of medication, a fall of 11.5 per cent. This change, while of limited significance, was not seen following administration of benzoic acid in a comparable manner.

In an attempt to determine possible mechanisms responsible for this difference the conjugation of bile acids in bile was studied. Following the administration of para-amino-benzoic acid and also nicotinic acid, there was an increase in the proportion of taurine to glycine conjugated bile acids. An opposite effect followed the administration of benzoic acid.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1962 by The American Society for Nutrition