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American Journal of Clinical Nutrition, Vol 11, 4-11, Copyright © 1962 by The American Society for Clinical Nutrition, Inc.

Bile Acid Excretion in Man Following Administration of L3:5:3' Triiodothyronine

ROBERT B. FAILEY JR. M.D.1, EARLENE BROWN PH.D.1, and M. E. HODES M.D., PH.D.1

1 From the Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana

Bile obtained by duodenal intubation of human subjects was analyzed for its bile acid content. Specific bile acids studied were cholic, chenodeoxycholic and deoxycholic. Following administration of L3:5:3' triiodothronine a decrease was noted in the ratio of chenodeoxycholic to cholic acid (CD:C). This change was maximal at two hours. It was not noted in bile obtained by choledochostomy drainage from patients with recent cholecystectomies.






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