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American Journal of Clinical Nutrition, Vol 12, 220-227, Copyright © 1963 by The American Society for Clinical Nutrition, Inc.

The Digestion of Carbohydrates in the Small Intestine

DAVID MILLER M.D.1 and ROBERT K. CRANE PH.D.1

1 From the Department of Biological Chemistry, Washington University School of Medicine, St. Louis, Missouri

The relative distribution of the products of in vitro hydrolysis of sucrose, maltose and glucose 1-phosphate between the tissue and the medium was measured in the small intestine of the hamster. The concentration relationships found indicate that hydrolysis of all three of these compounds takes place within the epithelial cells. The brush border membranes of the epithelial cell were isolated, and localization of invertase and maltase in these particles was demonstrated. The implications as to the role of the intestine in digestion are discussed.






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Copyright © 1963 by The American Society for Nutrition