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American Journal of Clinical Nutrition, Vol 13, 238-242, Copyright © 1963 by The American Society for Clinical Nutrition, Inc.

Effect of Vitamin E and Methyltestosterone Upon the Progeria-Like Syndrome Produced by Dihydrotachysterol

BEATRIZ TUCHWEBER L.PH.1, GIULIO GABBIANI M.D.1, and HANS SELYE M.D.,PH.D., D.SC.1

1 From the Institut de Médecine et de Chirurgie expérimentales, Université de Montréal, Montreal, Canada

Experiments on the rat indicate that the progeria-like syndrome induced by chronic intoxication with dihydrotachysterol can be prevented by concurrent d-agr-tocopheryl acetate treatment.

Methyltestosterone is equally effective, but no synergism could be demonstrated between vitamin E and the anabolic androgen.






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