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American Journal of Clinical Nutrition, Vol 16, 412-416, Copyright © 1965 by The American Society for Clinical Nutrition, Inc.
1 From the Research Service, Wood Veterans Administration Hospital, and the Departments of Pharmacology, Medicine and Physiology, Marquette University School of Medicine, Milwaukee, Wisconsin
Ten fasting subjects, who received 50 mg. heparin intravenously 30 minutes before ingestion of a high fat meal, responded with an immediate but brief rise in plasma unesterified fatty acid (UFA) levels. The subsequent lipemia was significantly higher than that which developed in a second comparable group of ten subjects who received the same high fat meal but no pretreatment with heparin. The pretreated subjects also showed reduced lipemia-clearing activity following a second dose of heparin administered 3 hours after the meal.
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