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American Journal of Clinical Nutrition, Vol 17, 51-54, Copyright © 1965 by The American Society for Clinical Nutrition, Inc.

Some Considerations of Celiac Disease

H. A. WEIJERS M.D.1 and J. H. VAN DE KAMER PH.D.1

1 From the Wilhelmina Children's Hospital, University of Utrecht, and the Central Institute for Nutrition and Food Research T.N.O., Zeist, The Netherlands

The importance of a gluten-free diet in understanding the diagnosis, pathogenesis, etiology, prognosis and therapy of celiac disease is discussed in an historic context. Emphasis is placed on the role of wheat sensitivity in the diagnosis of "idiopathic celiac disease," and such classic criteria as infantilism, dystrophy, bulky malodorous steatorrhea, general hypotonia and a negativistic psychic attitude are reviewed. Regarding the pathogenesis and etiology of the disease, the peptide hypothesis is mentioned briefly. The prognosis is entirely favorable if the patient adheres to a rigidly wheat-less diet. The composition of this diet is outlined broadly.






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Copyright © 1965 by The American Society for Nutrition