AJCN Tufts Nutrition Symposium, Boston Sept 24-26
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by BAKER, H.
Right arrow Articles by SOBOTKA, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by BAKER, H.
Right arrow Articles by SOBOTKA, H.
Agricola
Right arrow Articles by BAKER, H.
Right arrow Articles by SOBOTKA, H.

American Journal of Clinical Nutrition, Vol 17, 88-95, Copyright © 1965 by The American Society for Clinical Nutrition, Inc.

The Fate of Orally and Parenterally Administered Folates

HERMAN BAKER PH.D.1, OSCAR FRANK PH.D.1, SUSAN FEINGOLD B.S.1, HERMAN ZIFFER M.D.1, ROSEMARY A. GELLENE M.D.1, CARROLL M. LEEVY M.D.1, and HARRY SOBOTKA PH.D.1

1 From the Division of Hepatic Metabolism and Nutrition, Department of Medicine, New Jersey College of Medicine, Jersey City, New Jersey; the Department of Internal Medicine, Roosevelt Hospital, New York, New York; and the Department of Chemistry, Mt. Sinai Hospital, New York, New York

The fate of orally and parenterally administered folic acid, folinic acid, Diopterin and Teropterin was followed in serum and urine. Folate activities in serum and urine were charted by chromatography and bioautography, exploiting the differential folate responses of Lactobacillus casei, Pediococcus cerevisiae and Streptococcus faecalis. The outstanding findings are the conversion of ingested folinic acid into a folate inactive for P. cerevisiae and S. faecalis but active for L. casei and the conversion of orally administered Diopterin into an L. casei active folate, although Diopterin is inactive in vitro. Comparisons of the results obtained with serum and urine indicate that folic acid is the principal metabolic end product in the urine after pteroylmonoglutamate or pteroylpolyglutamate administration.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1965 by The American Society for Nutrition