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American Journal of Clinical Nutrition, Vol 19, 415-421, Copyright © 1966 by The American Society for Clinical Nutrition, Inc.

Zinc Levels and Blood Enzyme Activities in Egyptian Male Subjects with Retarded Growth and Sexual Development

Y. D. COBLE M.D.1, R. VANREEN M.D.1, A. R. SCHULERT M.D.1, R. P. KOSHAKJI M.D.1, Z. FARID M.D.1, and J. T. DAVIS M.D.1

1 From the Epidemiology, Medical and Biochemistry Departments, U. S. Naval Medical Research Unit No. 3, Cairo, U.A.R.; Nutrition Section, Office of International Research, NIH, Bethesda, Maryland; and Division of Nutrition, Vanderbilt University School of Medicine, Nashville, Tennessee

Zinc deficiency in animals results in a retardation of growth and sexual development. An attempt has been made during previous investigations to correlate low plasma zinc levels in rural male Egyptians with retarded growth and sexual development. Our present studies have revealed that plasma zinc levels in rural male Egyptians with normal maturation are also low. Normal Egyptians and Americans living in Cairo have normal plasma zinc levels. Egyptian "hypogonadal dwarfs" have been demonstrated to ultimately obtain sexual maturity and a normal stature without treatment or change in their low plasma zinc levels. Thus the significance of plasma zinc level as a reflection of maturation or zinc deficiency remains unclear.




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