American Journal of Clinical Nutrition, Vol 20, 126-130, Copyright © 1967 by The American Society for Clinical Nutrition, Inc.

Effect of Dietary Carbohydrate on the Glucose Tolerance Curve in the Normal and the Carbohydrate-Induced Hyperlipemic Subject

¹ From the Departments of Medicine B and A and the Isotope Laboratory for Endocrine Research of the Hadassah-Hebrew University Hospital and Medical School, Jerusalem, Israel

If sucrose is fed long enough and in appropriate quantities one can produce in either man or rat an impairment to the glucose tolerance. This response may be the background for the change in lipid metabolism observed in the sucrose-fed individuals, normal or hyperlipemic. Changing other dietary factors, such as the quantity of dietary protein or fat, may influence this impairment. Although this impairment is statistically significant in a group, individual variations are marked, and constitutional factors—enzymatic or hormonal—are to be considered in the response of the individual to this change.