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American Journal of Clinical Nutrition, Vol 20, 133-138, Copyright © 1967 by The American Society for Clinical Nutrition, Inc.

Dietary Carbohydrate and Fat, Serum Lipoproteins, and Human Atherosclerosis

J. A. LITTLE 1, H. M. SHANOFF 1, A. CSIMA 1, and R. Yano 1

1 From the Department of Medicine, St. Michael's and Sunnybrook Hospitals, University of Toronto, Canada

Serum lipids and lipoproteins were correlated with the habitual diets of healthy Canadian men and men with coronary heart disease. It had been shown previously that the serum lipids and lipoproteins were significantly higher in the coronary group and there were no important differences in the diets.

In the coronary group, total dietary fat correlated positively with serum cholesterol, phospholipid, and Std Sf 0-20 lipoproteins. Total carbohydrate and sucrose had no important correlation with these serum fractions or with Std Sf 20-400 lipoproteins. This suggests that, in the habitual diets of coronary-prone men, fats influence the serum lipid levels more than do carbohydrates.

In the control group, the same dietary factors tended to have a negative correlation with serum lipids and lipoproteins.

Coronary patients appear to be metabolically different with a susceptibility to hyperlipidemic foods.






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Copyright © 1967 by The American Society for Nutrition