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American Journal of Clinical Nutrition, Vol 20, 783-789, Copyright © 1967 by The American Society for Clinical Nutrition, Inc.

Hematologic Response to Vitamin E in the Anemia Associated with Protein-Calorie Malnutrition

JO ANNE WHITAKER M.D.1, ELEANOR G. FORT B.S.1, SERENE VIMOKESANT D.SC.1, and JAMES S. DINNING PH.D.1

1 From the Department of Pediatrics, Chiengmai Hospital, University of Chiengmai, Chiengmai, Thailand

Hematologic data from 60 children with anemia associated with protein-calorie malnutrition in Chiengmai, Thailand, are presented and discussed. The patients were divided into two groups, group I (41 cases) receiving a hospital high protein diet only, and group II (19 cases) receiving, in addition to protein, 250 µg of vitamin E orally for 5 days.

Children receiving only protein became progressively anemic while those treated with vitamin E demonstrated a statistically significant rise in reticulocyte and hemoglobin levels. General clinical improvement associated with rising total proteins and increase in body weight occurred in both groups I and II.

It is recognized that this is an anemia of multiple etiology but the results presented demonstrate a consistent hematologic response to treatment with vitamin E.






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Copyright © 1967 by The American Society for Nutrition