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American Journal of Clinical Nutrition, Vol 20, 795-798, Copyright © 1967 by The American Society for Clinical Nutrition, Inc.

Relationship between Plasma Vitamin E Level and Peroxide Hemolysis Test in Human Subjects

P. J. LEONARD M.SC., PH.D.1 and M. S. LOSOWSKY M.D., M.R.C.P.1

1 From the Department of Medicine, The University of Leeds, The General Infirmary, Leeds, England

The relationship between the plasma vitamin E level and the results of the peroxide hemolysis test was studied in 233 subjects. It was confirmed that the hemolysis test is a useful index of plasma vitamin E levels.

A negative test strongly suggests a plasma level above 0.3 mg/100 ml and hemolysis in excess of 10% strongly suggests a plasma level below this value. Intermediate levels of hemolysis are a less certain guide to the plasma level.

It is suggested that in view of its simplicity the hemolysis test is of considerable value as a screening procedure.






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Copyright © 1967 by The American Society for Nutrition