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American Journal of Clinical Nutrition, Vol 20, 808-815, Copyright © 1967 by The American Society for Clinical Nutrition, Inc.

Relationship between Total Cholesterol and Cholesteryl Esters with Age in Human Blood Plasma

A. LOPEZ M.D., PH.D.1, W. A. KREHL M.D., PH.D.1, and R. E. HODGES M.D.1

1 From University of Iowa, College of Medicine, Department of Internal Medicine, Iowa City, Iowa

The concentration of total cholesterol and different cholesteryl esters has been determined in a group of 2,691 individuals.

There was an increase in the total serum cholesterol content and in the esterified fraction with advancing age.

The annual change (in milligrams/100 ml) of total cholesterol, was found to be larger than the annual change of total ester.

No significant differences were found between sexes in regard to the changes with age of the esterified fraction of cholesterol. Changes in the esterified fraction of cholesterol occured with age in both sexes.

A highly positive correlation was observed between total and esterified cholesterol and between cholesteryl linoleate and total esterified cholesterol. A high negative correlation was observed between cholesteryl esters of saturated fatty acids and cholesteryl linoleate.




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