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American Journal of Clinical Nutrition, Vol 21, 1341-1344, Copyright © 1968 by The American Society for Clinical Nutrition, Inc.

Impairment of Thiamine Absorption in Alcoholism

P. A. TOMASULO 1, R. M. H. KATER M.B., M.R.A.C.P.1, and F. L. IBER M.D.1

1 From the Alcoholism Unit, Johns Hopkins University versity School of Medicine, Johns Hopkins Hospital, and Baltimore City Hospitals, Baltimore, Maryland

A controlled study of radioactive thiamine absorption in severe alcoholics who had been drinking just prior to the study is reported.

A highly significant impairment of thiamine absorption was found in the 20 alcoholics as compared with 10 nonalcoholic controls.

It is suggested that malabsorption of thiamine plays a greater role in the production of alcoholic thiamine deficiency than is generally appreciated.




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