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American Journal of Clinical Nutrition, Vol 21, 1366-1373, Copyright © 1968 by The American Society for Clinical Nutrition, Inc.

Ingested Glucose and Fructose in Serum Lipids in Healthy Men and after Myocardial Infarction

IAN MACDONALD M.D., PH.D., D.SC.1

1 From the Department of Physiology, Guy's Hospital Medical School, London, S.E.1, England

In order to determine whether the incorporations, into serum lipids, of dietary fructose and glucose were similar, the generally labeled 14C isotope of each monosaccharide in 25 g of the carbohydrate was ingested, after a 10-hr fast, by 5 healthy men and by 10 men who had had a myocardial infarct.

The specific activity of the serum triglycerides was greater after the ingestion of 14C-fructose than after 14C-glucose, in both groups, suggesting that fructose is preferred to glucose by the lipid synthetic pathways in the fasted state. When glucose was given, the specific activity of the serum triglycerides, when compared with control, was greater after a myocardial infarct.




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J. P Bantle, S. K Raatz, W. Thomas, and A. Georgopoulos
Effects of dietary fructose on plasma lipids in healthy subjects
Am. J. Clinical Nutrition, November 1, 2000; 72(5): 1128 - 1134.
[Abstract] [Full Text] [PDF]


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