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American Journal of Clinical Nutrition, Vol 21, 230-244, Copyright © 1968 by The American Society for Clinical Nutrition, Inc.

The Role of Chromium in Mammalian Nutrition

HENRY A. SCHROEDER M.D.1

1 From the Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire, and Brattleboro Memorial Hospital, Brattleboro, Vermont

There is enough experimental evidence on chromium to classify it as an essential micronutrient for mammals concerned with carbohydrate and lipid metabolism. Data from 31 areas of the world indicate that tissues of many Americans but few foreigners were deficient in chromium. Lacking are definitive experiments linking the disorders found in chromium-deficient laboratory animals and their human counterparts, hypercholesteremia, atherosclerosis, and diabetes mellitus. At the present stage of knowledge, the hypothesis that atherosclerosis and some forms of diabetes mellitus are partly the result of chromium deficiency deserves exploration.




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H. W. Staub, G. Reussner, and R. Thiessen Jr.
Serum Cholesterol Reduction by Chromium in Hypercholesterolemic Rats
Science, November 7, 1969; 166(3906): 746 - 747.
[Abstract] [PDF]




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Copyright © 1968 by The American Society for Nutrition