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American Journal of Clinical Nutrition, Vol 22, 14-20, Copyright © 1969 by The American Society for Clinical Nutrition, Inc.

Fat and Nitrogen Balance with Medium-Chain Triglycerides after Massive Intestinal Resection

KAROLY G. PINTER M.D., PH.D.1, HARRIS HYMAN III M.D.1, and OSCAR BOLANOS M.D.1

1 From the Department of Medicine, Nutrition-Metabolism Research Laboratories, Tulane University School of Medicine, New Orleans, Louisiana 70112

Three patients with massive intestinal resection were studied to determine the effect of substituting medium-chain triglycerides for long-chain triglycerides on fat and nitrogen balance. On the medium-chain triglyceride-supplemented diet there was a reduction of steatorrhea and there was also an improvement in nitrogen balance. The abnormally low serum lipids were improved. The patients with diarrhea experienced a decrease in the number of bowel movements. The possible causes for these results are suggested to be decreased intestinal motility, improved proteolysis in the gut, and the beneficial effects of protein sparing by the greater number of available calories for the maintainance of homeostasis.






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Copyright © 1969 by The American Society for Nutrition