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American Journal of Clinical Nutrition, Vol 22, 5-7, Copyright © 1969 by The American Society for Clinical Nutrition, Inc.

Variability of Plasma Phospholipids in Normal Adults

WILLIAM H. R. NYE M.D.1

1 From the Department of Medicine, University of Rochester, Rochester, New York 14620

Plasma lipids are known to be influenced by dietary history and by other environmental factors. To assess the amount of variation that occurs in phospholipid composition, individual plasma phospholipids have been determined serially under strict dietary control, employing eight dietary periods and two normal subjects. Coefficients of variations of serial samples frequently exceed cv's of replicate analyses, but are of the same order or magnitude as cv's of other biological variables. Mean sphingomyelin and lecithin vary at times with changes in diet. Proportions among the individual plasma phospholipids are thus not as stable as has been generally thought.






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Copyright © 1969 by The American Society for Nutrition