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American Journal of Clinical Nutrition, Vol 22, 431-436, Copyright © 1969 by The American Society for Clinical Nutrition, Inc.

Vitamin D-Induced Calcium-Binding Protein of Intestinal Muscosa

Relation to Vitamin D Dose Level and Lag Period

J. G. EBEL 1, A. N. TAYLOR 1, and R. H. WASSERMAN 1

1 From the Department of Physical Biology, New York State Veterinary College, Cornell University, Ithaca, New York 14850

As a result of time studies (0-48 hr) with rachitic chicks given crystalline vitamin D3 at a dose range of 0-100,000 IU, it has been possible to establish a correlation between a change in calcium absorption (duodenal loops) and the appearance and relative amount of the vitamin D-induced calcium-binding protein in mucosal tissue. Although it is not yet known where and by what mechanism CaBP functions at a cellular level, available evidence is fully consistent with a role of CaBP in calcium transport.






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Copyright © 1969 by The American Society for Nutrition