AJCN Tufts Nutrition Symposium, Boston Sept 24-26
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American Journal of Clinical Nutrition, Vol 22, 559-567, Copyright © 1969 by The American Society for Clinical Nutrition, Inc.

Ocular Lesions in Scurvy

JAMES HOOD 1 and ROBERT E. HODGES 1

1 From The Department of Internal Medicine, University Hospitals, Iowa City, Iowa

Despite the recorded rarity of ocular vascular lesions in human scurvy, conjunctival lesions appeared during deprivation of ascorbic acid in five of nine volunteers who participated in two studies of experimental scurvy in man, three of four men in the first study and two of five men in the second. The ocular lesions often appeared early in the development of clinical scurvy and were first noted after deprivation of ascorbic acid for 74-95 days.

These lesions varied from minute bulbar conjunctival hemorrhages and varicosities to a large subconjunctival hemorrhage accompanied by palpebral petechial hemorrhages, and conjunctival congestion.




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