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American Journal of Clinical Nutrition, Vol 22, 710-715, Copyright © 1969 by The American Society for Clinical Nutrition, Inc.
1 From the Departments of Medicine and Dietetics, St. Michael's Hospital, University of Toronto, Toronto, Ontario
The effect of adding pure cholesterol to a formula diet with corn oil (35% of calories), as the only fat source, was studied in five patients with hyperlipidemia. It was found that 1,000 mg cholesterol/day significantly interfered with the cholesterol-lowering effect of the diet. In spite of the ingestion of large amounts of corn oil by the hyperlipidemic subjects, the effect of the dietary cholesterol on serum cholesterol conformed with the predictive formula described by Keys and co-workers (9).
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