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American Journal of Clinical Nutrition, Vol 23, 514-519, Copyright © 1970 by The American Society for Clinical Nutrition, Inc.

Zinc and Wound Healing

Effects of Zinc Deficiency and Zinc Supplementation

HAROLD H. SANDSTEAD M.D.1, VERNE C. LANIER JR. M.D.1, GLENN H. SHEPHARD M.D.1, and DAVID D. GILLESPIE B.A.1

1 From the Division of Nutrtion and Department of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37203

The rate of closure of defects in the integument (surgical or thermal) and the tensile strength of healing wounds are decreased by zinc deficiency in the rat.

Zinc supplementation of normal rats will not improve the rate of closure or the tensile strength of wounds in the integument.




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Y. Lim, M. Levy, and T. M. Bray
Dietary Zinc Alters Early Inflammatory Responses during Cutaneous Wound Healing in Weanling CD-1 Mice
J. Nutr., April 1, 2004; 134(4): 811 - 816.
[Abstract] [Full Text] [PDF]


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