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American Journal of Clinical Nutrition, Vol 23, 779-781, Copyright © 1970 by The American Society for Clinical Nutrition, Inc.

Influence of Succinic Acid on Absorption of Iron Studied by Whole-Body Monitoring

GEORGE WILL B.SC., M.B., F.R.C.P.G., M.R.C.P.E.1 and KEITH BODDY B.SC., M.SC., PH.D., F. INST. P.2

1 Consultant Physician, Gateside Hospital, Greenock, Scotland
2 Senior Lecturer, Scottish Research Reactor Centre, East Kilbride

Nineteen normal adult male volunteers were given two 10-day courses of oral ferrous succinate, one course being given with added free succinic acid, the other without. Each dose contained 37 mg elemental iron. Iron absorption was measured using a whole-body monitor.

The addition of free succinic acid did not lead to an increase in the whole-body absorption of iron. In nine subjects in whom the red cell incorporation of iron was measured, iron utilization was not increased by the addition of free succinic acid.






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Copyright © 1970 by The American Society for Nutrition