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American Journal of Clinical Nutrition, Vol 23, 1059-1068, Copyright © 1970 by The American Society for Clinical Nutrition, Inc.

Meal Frequency—A Possible Factor in Human Pathology

PAVEL FÁBRY M.D., D.SC.1 and JAY TEPPERMAN M.D.1

1 From the Department of Pharmacology, State University of New York, Upstate Medical Center, Syracuse, New York 13210

Epidemiological studies revealed that excessive weight and, in elderly age groups, also hypercholesterolemia, impaired glucose tolerance, and ischemic heart disease was more common among persons with an infrequent meal pattern than among those who customarily ate five or more meals per day. Factors involved in the mechanism of metabolic effects of infrequent feeding are discussed especially with respect to possible pathogenic effects of infrequent feeding in man.




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