AJCN Tufts Nutrition Symposium, Boston Sept 24-26
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American Journal of Clinical Nutrition, Vol 25, 16-22, Copyright © 1972 by The American Society for Clinical Nutrition, Inc.

Effect of hydrogenated soybean fat on rat adipose tissue and on liver acetyl-CoA carboxylase and fatty acid synthetase activities

Peter O. Egwim 1 and Demetrios S. Sgoutas 1

1 From The Burnsides Research Laboratory, University of Illinois, Urbana, Illinois 61801

The activities of fatty acid synthetase and acetyl-CoA carboxylase in vitro were measured in adipose tissue and liver of male rats fed partially hydrogenated soybean fat, supplemented or not with 2% corn oil, for 6.5 weeks. Control groups of rats were fed diets containing 12 and 22% corn oil, respectively. Relative to the control groups, the observed responses (depressed or enhanced activities) varied with the type of tissue, being more marked with adipose tissue enzymes than with liver enzymes. Possible reasons for these observations were discussed from the standpoint of EFA and trans fatty acid contents of the diets and tissues.






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Copyright © 1972 by The American Society for Nutrition