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American Journal of Clinical Nutrition, Vol 25, 265-268, Copyright © 1972 by The American Society for Clinical Nutrition, Inc.

Effect of hepatic disease on liver flavin and protein levels

William J. Jusko Ph.D.1 and George P. Lewis M.D., M.R.C.P.1

1 From the Section of Clinical Pharmacology, Veterans Administration Hospital, Boston, Massachusetts 02130

Autopsy specimens of liver and renal cortex tissue were obtained from 170 patients. Total flavins showed excellent correlation with protein levels in both tissues. Patients with cirrhosis had deficient hepatic levels of flavins and protein but renal levels were normal, whereas renal disease did not affect the levels of the vitamin. Treatment of patients with multiple vitamins prior to death had no apparent effect on hepatic and renal flavin leve1s.






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Copyright © 1972 by The American Society for Nutrition