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American Journal of Clinical Nutrition, Vol 25, 756-762, Copyright © 1972 by The American Society for Clinical Nutrition, Inc.
1 From the United States Army Medical Research and Nutrition Laboratory, Fitzsimons General Hospital, Denver, Colorado 80240, and the Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37203
Glutathione reductase activity coefficients were measured on blood samples obtained from 431 Tennessee high school students as a means of evaluating their riboflavin nutritional status. With the use of this technique, 11.1% of the students were considered to have an inadequate intake of riboflavin. The incidence was higher among the girls (16.0%) than the boys (6.1 %), with the highest incidence occurring among the black girls (37.9%). Riboflavin supplementation of 5 mg/day for 1 week corrected abnormal EGR activity coefficients. The procedure appears to be an additional useful technique for evaluating riboflavin adequacy in nutrition surveys or in clinical cases with suspected deficiency.
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