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American Journal of Clinical Nutrition, Vol 26, 340-346, Copyright © 1973 by The American Society for Clinical Nutrition, Inc.

The role of pancreatic exocrine secretions in the absorption of vitamin B12 and iron

Leslie Bernstein M.D.1 and Victor Herbert M.D.1

1 From the Division of Gastroenterology, Department of Medicine, Montefiore Hospital, and Albert Einstein College of Medicine; and the Department of Medicine, Veterans Administration Hospital, Bronx, N.Y. 10468, and the Department of Pathology, Columbia University College of Physicians and Surgeons, New York, N.Y. 10032

Pancreatic dysfunction is associated with decreased absorption of B12 and increased absorption of iron. The decreased B12 absorption is reproducibly improved by oral therapy with pancreatic exocrine secretions (pancreatin or bicarbonate, or both); increased iron absorption is not as reproducibly improved by such oral therapy. The specific roles of pancreatic exocrine secretions in absorption of B12 and iron await greater elucidation by further research.






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Copyright © 1973 by The American Society for Nutrition