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American Journal of Clinical Nutrition, Vol 26, 487-490, Copyright © 1973 by The American Society for Clinical Nutrition, Inc.
1 From the Departments of Medicine, Biochemistry, and Surgery, Emory University School of Medicine, and the Clinical Research Facility, Emory University Hospital, Atlanta, Georgia 30322
Sixty-four foods were analyzed for ammonia (NH3) content. In 16 foods, NH3 constituted 3 to 23% of total nitrogen; in 22 foods, the proportion was 1 to 3%; in 26, the proportion was less than 1%.
The smallest quantity of dietary NH3 in the form of ammonium chloride required to increase blood NH3 concentration over 150 µg/100 ml was measured in 32 cirrhotic patients with a history of encephalopathy. This quantity was 0.04 g NH3 or less per 50 kg body wt in eight subjects.
One serving of eight of the foods studied contains 0.04 g NH3 or more. The data thus indicate that ingestion of preformed NH3 in certain foods contributes to hyperammonemia in cirrhotic patients.
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