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American Journal of Clinical Nutrition, Vol 27, 1225-1230, Copyright © 1974 by The American Society for Clinical Nutrition, Inc.

Riboflavin status in pregnancy

Sigfried Heller 1, Richard M. Salkeld 1, and Wilhelm F. Körner 1

1 From the University Obstetric Clinic, Tubingen, Germany and the Department of Vitamin and Nutrition Research, F. Hoffmann-La Roche & Co., Ltd., Basle, Switzerland

The riboflavin status in 651 pregnant women was determined by means of the erythrocyte glutathione reductase activation test. Although there was no significant correlation between the riboflavin status and the course or outcome of pregnancy, 25% of the pregnant women in the first trimester-increasing to 40% at term-were shown to be significantly riboflavin-depleted in comparison to a group of over 300 male and female blood donors. Riboflavin supplementation is therefore recommended to maintain normal coenzyme saturation of riboflavin enzymes.




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Copyright © 1974 by The American Society for Nutrition