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American Journal of Clinical Nutrition, Vol 27, 1441-1449, Copyright © 1974 by The American Society for Clinical Nutrition, Inc.

Contribution of the K88 antigen of Escherichia coli to enteropathogenicity; protection against disease by neutralizing the adhesive properties of K88 antigen

G. W. Jones Ph.D.1 and J. M. Rutter B.V.M.S., Ph.D.1

1 From the Department of Microbiology, Agricultural Research Council, Institute for Research on Animal Diseases, Compton, Newbury, Berkshire, England

The adhesive properties of K88 antigen and its contribution to the enteropathogenic character of K88-positive Escherichia coli are briefly discussed. Factors that may be involved in the protection of piglets from dams vaccinated with bacteria-free K88 antigen have been examined, and on the basis of in vitro tests, it is concluded that a significant protective effect is due to an antiadhesive factor in the colostrum of vaccinated sows.






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Copyright © 1974 by The American Society for Nutrition