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American Journal of Clinical Nutrition, Vol 27, 681-687, Copyright © 1974 by The American Society for Clinical Nutrition, Inc.
1 From the Division of Hematology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195
Serum ferritin has been measured by a two-site immunoradiometric assay employing antibody-coated polystyrene tubes. Normal values were established by performing measurements in male and female subjects between 20 and 50 years of age in whom iron-deficient erythropoiesis was excluded on the basis of transferrin saturation and red cell protoporphyrin. The serum ferritin was log-normally distributed with a geometric mean of 94 ng/ml in 174 males and 34 ng/ml in 152 females. Additional studies were performed in 83 healthy women to determine the relationship between serum ferritin and iron stores measured by radioiron absorption. A high correlation between these measurements indicates that the serum ferritin is a useful survey tool for the initial assessment and prospective monitoring of iron stores in a normal population.
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