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American Journal of Clinical Nutrition, Vol 28, 1234-1236, Copyright © 1975 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Lack of effect of massive dose of vitamin C on fluoride excretion in fluorosis during a short clinical trial

KA Krishnamachari and N Laxmaiah

The effect of daily administration of 2 g of vitamin C on urinary excretion of fluoride in patients suffering from endemic fluorosis was studied. Urinary fluoride excretion was found to be constant over a period of 4 weeks in each patient. The results suggested that vitamin C does not influence the rate of resorption of fluorotic bone in man.


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G. B. Reddy, A. L. Khandare, P. Y. Reddy, G. S. Rao, N. Balakrishna, and I. Srivalli
Antioxidant Defense System and Lipid Peroxidation in Patients with Skeletal Fluorosis and in Fluoride-Intoxicated Rabbits
Toxicol. Sci., April 1, 2003; 72(2): 363 - 368.
[Abstract] [Full Text] [PDF]


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Copyright © 1975 by The American Society for Nutrition