AJCN Tufts Nutrition Symposium, Boston Sept 24-26
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gross, R. L.
Right arrow Articles by Hift, W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gross, R. L.
Right arrow Articles by Hift, W.
Agricola
Right arrow Articles by Gross, R. L.
Right arrow Articles by Hift, W.

American Journal of Clinical Nutrition, Vol 28, 225-232, Copyright © 1975 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Depressed cell-mediated immunity in megaloblastic anemia due to folic acid deficiency

RL Gross, JV Reid, PM Newberne, B Burgess, R Marston and W Hift

Cell-mediated immunity has been studied in patients with 1) megaloblastic anemia of folic acid deficiency, 2)megaloblastic anemia of pregnancy, or 3) iron-deficiency anemia. Using dinitrochlorobenzene skin tests, phytohemagglutinin-stimulated lymphocyte transformation, and rosette inhibition by antilymphocyte globulin, we have shown that cell-mediated immunity is depressed in megaloblastic anemia due to folate deficiency; this depression was reversed by folate treatment. Cell-mediated immunity was not impaired by iron-deficiency anemia. Suggested interactions between iron deficiency and folate metabolism were not clarified by these studies.


This article has been cited by other articles:


Home page
 Am. J. Clin. Nutr.Home page
P. K Drain, R. Kupka, F. Mugusi, and W. W Fawzi
Micronutrients in HIV-positive persons receiving highly active antiretroviral therapy
Am. J. Clinical Nutrition, February 1, 2007; 85(2): 333 - 345.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
R. R. Molls, N. Ahluwalia, A. M. Mastro, H. Smiciklas-Wright, and G. C. Handte
Nutritional Status Predicts Primary Subclasses of T Cells and the Lymphocyte Proliferation Response in Healthy Older Women
J. Nutr., November 1, 2005; 135(11): 2644 - 2650.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
N. Ahluwalia, J. Sun, D. Krause, A. Mastro, and G. Handte
Immune function is impaired in iron-deficient, homebound, older women
Am. J. Clinical Nutrition, March 1, 2004; 79(3): 516 - 521.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
Y.-I. Kim, M. Hayek, J. B. Mason, and S. N. Meydani
Severe Folate Deficiency Impairs Natural Killer Cell-Mediated Cytotoxicity in Rats
J. Nutr., June 1, 2002; 132(6): 1361 - 1367.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
S. R. Kuvibidila, C. Porretta, and B. S. Baliga
Iron Deficiency Alters the Progression of Mitogen-Treated Murine Splenic Lymphocytes through the Cell Cycle
J. Nutr., July 1, 2001; 131(7): 2028 - 2033.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1975 by The American Society for Nutrition