AJCN Tufts Nutrition Symposium, Boston Sept 24-26
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American Journal of Clinical Nutrition, Vol 29, 1461-1467, Copyright © 1976 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

The binding of the components of mixed micelle to dietary fiber

M Eastwood and L Mowbray

Bile acid conjugates are adsorbed to cereal fiber. Bile acid conjugates incorporated into micelles with cholesterol are reversibly adsorbed as micelles on to the fiber. Incorporating bile acid conjugates into micelles with monoglycerides somewhat depresses adsorption of bile acid conjugate. If fatty acids, monoglycerides, and bile acid conjugate mixed micelles are exposed to cereal fiber, then adsorption of bile acids to the fiber is diminished. The extent to which the adsorption is diminished is affected by the fatty acid concentration, chain length, and unsaturation. This suggests that bile acid conjugates are minimally adsorbed to fiber in the jejunum but deconjugation and dehydroxylation as in the cecum favors adsorption.




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Copyright © 1976 by The American Society for Nutrition