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American Journal of Clinical Nutrition, Vol 31, 574-578, Copyright © 1978 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Changes in the red blood cell membrane in protein-calorie malnutrition

KH Brown, RM Suskind, B Lubin, P Kulapongs, C Leitzmann and RE Olson

Ten children with protein-calorie malnutrition (five with kwashiorkor, three with marasmus, and two with marasmic-kwashiorkor) were studied at hospital admission and during recovery for evidence of changes in red blood cell lipids, osmotic fragility, and chromium survival. On admission, the children had significantly higher-than-normal red blood cell membrane cholesterol and phospholipid, and an elevated cholesterol:phospholipid ratio. Both red blood cell osmotic fragility and red cell survivals were depressed. These measurements returned to normal limits with recovery.


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Copyright © 1978 by The American Society for Nutrition