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American Journal of Clinical Nutrition, Vol 31, 1322-1327, Copyright © 1978 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
VS Nagabhushan and BS Narasinga Rao
Twenty-four hour urinary excretion of 3-methylhistidine (3-MeHis) was determined in children suffering from severe and moderate degrees of protein-energy malnutrition before and after treatment. Excretion of 3- MeHis was decreased both in children with severe protein-energy malnutrition and during undernutrition and increased considerably after treatment. The results suggest that there is a quantitative as well as a qualitative change in 3-MeHis metabolism in protein-energy malnutrition. A sensitive index for studying muscle protein metabolism is not available so far. Studies reported herein seem to suggest that 3- MeHis may fulfill such a requirement.
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C.-W. Kim, A. Okada, T. Itakura, Y. Takagi, K. Nakao, and Y. Kawashima Urinary Excretion of 3-Methylhistidine as an Index of Protein Nutrition in Total Parenteral Nutrition JPEN J Parenter Enteral Nutr, March 1, 1988; 12(2): 198 - 204. [Abstract] [PDF] |
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