AJCN EB 2010
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American Journal of Clinical Nutrition, Vol 31, 1642-1646, Copyright © 1978 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Digestive-absorptive function of the intestinal brush border in uremia

V Wizemann, D Ludwig, R Kuhl and I Burgmann

Amino acid absorption was studied in chronic uremic rats. Intestinal transport of L-leucine appears to be inhibited with mild uremic intoxication, whereas severe uremia enhances absorption. Brush border activity of intestinal maltase and disaccharidases is higher in rats with chronic renal insufficiency. The same holds for gamma-glutamyl- transpeptidase activity.


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Y. Shimizu, S. Masuda, K. Nishihara, L. Ji, M. Okuda, and K.-i. Inui
Increased protein level of PEPT1 intestinal H+-peptide cotransporter upregulates absorption of glycylsarcosine and ceftibuten in 5/6 nephrectomized rats
Am J Physiol Gastrointest Liver Physiol, April 1, 2005; 288(4): G664 - G670.
[Abstract] [Full Text] [PDF]


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Copyright © 1978 by The American Society for Nutrition