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American Journal of Clinical Nutrition, Vol 32, 2346-2353, Copyright © 1979 by The American Society for Clinical Nutrition, Inc


ORIGINAL RESEARCH COMMUNICATIONS

Folacin and iron status and hematological findings in predominately black elderly persons from urban low-income households

LB Bailey, PA Wagner, GJ Christakis, PE Araujo, H Appledorf, CG Davis, J Masteryanni and JS Dinning

The folacin and iron status and hemotological parameters of 193 persons 60 years of age and older from urban low-income households were evaluated. Of the serum folacin values 30% were between 3 and 6 ng/ml and 8% were below 3 ng/ml. Of these subjects 60% could be classified as "high risk" (less than 140 ng/ml) and 11% as "medium risk" (140 to 160 ng/ml) based on red blood cell folacin concentrations. Serum iron was normal (greater than 50 micrograms/dl) for all subjects as was transferrin saturation (greater than 15%). Hematological indices showed a 14% incidence of anemia (hemaglobin less than 12 g/dl), and 32% incidence of leukopenia (leukocytes less than 4.8 X 10(3)). These findings demonstrate widespread folacin deficiency and no evidence of iron deficiency in these elderly people.


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Proc. Natl. Acad. Sci. USAHome page
B. C. Blount, M. M. Mack, C. M. Wehr, J. T. MacGregor, R. A. Hiatt, G. Wang, S. N. Wickramasinghe, R. B. Everson, and B. N. Ames
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage
PNAS, April 1, 1997; 94(7): 3290 - 3295.
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