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American Journal of Clinical Nutrition, Vol 32, 550-552, Copyright © 1979 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
JS Prasad
Production of hydrogenperoxide and myeloperoxidase-mediated iodination, by leucocytes was studied in normal subjects and subjects suffering from iron-deficiency anemia. The leucocytes obtained from severe cases of iron-deficiency anemia showed decreased myeloperoxidase-mediated iodination. Defective myeloperoxidase-mediated iodination can explain the basis for the leucocyte microbicidal defect in iron deficiency anemia.
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