American Journal of Clinical Nutrition, Vol 32, 1670-1678, Copyright © 1979 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Triglyceride integrated concentrations: effect of variation of source and amount of dietary carbohydrate

JT Hayford, MM Danney, D Wiebe, S Roberts and RG Thompson

The effect of changes in the amount of dietary carbohydrate (45 or 65% of total energy) and in the source of carbohydrate (sucrose or corn syrup) on plasma triglyceride and cholesterol concentrations was studied in eight healthy males. Subjects ingested each of the four formula diets for 10 days in a latin square sequence. Diet-induced response was assessed by measurement of plasma lipid concentrations in blood obtained after overnight fast and by measurement of the mean plasma lipid concentrations--designated the integrated concentration-- of blood obtained by 24 hr continuous blood withdrawal. The fasting plasma triglyceride concentration increased significantly during ingestion of the high carbohydrate diet (P less than 0.005) but was not significantly influenced by the source of carbohydrate calories. The 45% carbohydrate diets induced larger meal associated plasma triglyceride variation than 65% diets. Sucrose-containing diets induced significantly higher plasma triglyceride integrated concentrations than corn syrup diets, whether provided as 45% (P less than 0.05) or 65% (P less than 0.005) of total energy. Diet-induced changes in fasting or integrated plasma cholesterol concentration were minimal.

This article has been cited by other articles:

				J. Busserolles, E. Gueux, E. Rock, A. Mazur, and Y. Rayssiguier Substituting Honey for Refined Carbohydrates Protects Rats from Hypertriglyceridemic and Prooxidative Effects of Fructose J. Nutr., November 1, 2002; 132(11): 3379 - 3382. [Abstract] [Full Text] [PDF]

				R. Thompson, J. Hayford, and J. Hendrix Triglyceride concentrations: the disaccharide effect Science, November 16, 1979; 206(4420): 838 - 839. [Abstract] [PDF]