AJCN Tufts Nutrition Symposium, Boston & Online Sept 2009
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Duchateau, J.
Right arrow Articles by Vereecke, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Duchateau, J.
Right arrow Articles by Vereecke, P.
Agricola
Right arrow Articles by Duchateau, J.
Right arrow Articles by Vereecke, P.

American Journal of Clinical Nutrition, Vol 34, 88-93, Copyright © 1981 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Influence of oral zinc supplementation on the lymphocyte response to mitogens of normal subjects

J Duchateau, G Delespesse and P Vereecke

Oral zinc sulfate was given for 1 month to 83 normal subjects distributed in four groups according to age (20 to 40; 40 to 60), sex, and oral contraception. Their in vitro lymphocyte response to phytohemagglutinin and Concanavalin A, and their serum zinc and copper levels were measured before and after treatment. They were compared in 20 untreated subjects. Zinc treatment significantly increased the lymphocyte response to phytohemagglutinin and Concanavalin A. In the group of women aged 40 to 60, this resulted in a normalisation of the response to Concanavalin A. The response to zinc was related to the starting value of lymphocyte stimulation obtained by phytohemagglutinin, i.e., in low responders this was enhanced whereas in high responders it tended to be reduced. Treatment increased serum zinc and had no effect on serum copper. There was no correlation between serum zinc or copper and the lymphocyte response. The beneficial effect of zinc supplementation on the lymphocyte response does not result from a correction of latent zinc deficiency.


This article has been cited by other articles:


Home page
 Am. J. Clin. Nutr.Home page
N. M Lowe, K. Fekete, and T. Decsi
Methods of assessment of zinc status in humans: a systematic review
Am. J. Clinical Nutrition, June 1, 2009; 89(6): 2040S - 2051S.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
T. H. Karlsen, H. Sommerfelt, S. Klomstad, P. K. Andersen, T. A. Strand, R. J. Ulvik, C. Ahren, and H. M. S. Grewal
Intestinal and Systemic Immune Responses to an Oral Cholera Toxoid B Subunit Whole-Cell Vaccine Administered during Zinc Supplementation
Infect. Immun., July 1, 2003; 71(7): 3909 - 3913.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
N. Bhandari, R. Bahl, S. Taneja, T. Strand, K. Molbak, R. J. Ulvik, H. Sommerfelt, and M. K. Bhan
Substantial Reduction in Severe Diarrheal Morbidity by Daily Zinc Supplementation in Young North Indian Children
Pediatrics, June 1, 2002; 109(6): e86 - 86.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
L. Rink and H. Kirchner
Zinc-Altered Immune Function and Cytokine Production
J. Nutr., May 1, 2000; 130(5): 1407S - 1411.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1981 by The American Society for Nutrition