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American Journal of Clinical Nutrition, Vol 34, 2493-2498, Copyright © 1981 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Hypouricemia--a transient biochemical phenomenon of total parenteral nutrition

RL Koretz

A retrospective chart review of total parenteral nutrition identified several patients who developed hypouricemia. In order to study this phenomenon, seven patients were prospectively investigated during courses of total parenteral nutrition with serum and 24-h urine determinations of uric acid. In all seven patients, the serum uric acid level decreased, with the average fall being 3 mg/100 ml, then began to rise again. A uricosuric mechanism may have accounted for the reduced serum levels in one patient. The reduction in the serum uric acid in most patients is more likely related to a lowered rate of uric acid production.


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 JPEN J Parenter Enteral NutrHome page
V. Batuman, A. Dreisbach, J. K. Maesaka, M. Rothkopf, and E. Ross
Renal and Electrolyte Effects of Total Parenteral Nutrition
JPEN J Parenter Enteral Nutr, September 1, 1984; 8(5): 546 - 551.
[Abstract] [PDF]


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Copyright © 1981 by The American Society for Nutrition