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American Journal of Clinical Nutrition, Vol 34, 278-280, Copyright © 1981 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
DM Danks
A method of diagnosing trace metal deficiency is proposed. Measurement of an appropriate metalloprotein before and after administration of a physiological replenishment dose of the metal should distinguish low levels due to metal deficiency from those due to other mechanisms. Serum ceruloplasmin is the logical protein for copper assessment; serum alkaline phosphatase and red cell carbonic anhydrase should be considered for zinc.
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