| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
American Journal of Clinical Nutrition, Vol 34, 393-399, Copyright © 1981 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
RL Weinsier and CL Krumdieck
Although cachectic patients are relatively well adapted to their calorically deprived state, they are prone to acute metabolic imbalances when infused with hypertonic solutions of dextrose and amino acids. Of particular concern is hypophosphatemia and its associated disorders of cardiac, pulmonary, hematological, and neuromuscular functions. This report describes two chronically malnourished but stable patients who were given aggressive total parenteral nutrition support, which was rapidly followed by acute cardiopulmonary decompensation associated with severe hypophosphatemia and other metabolic abnormalities. Despite attempts at correction, progressive multiple systems failure led to death. In light of the high prevalence of hospital malnutrition and the ready availability of total parenteral nutrition, attention is brought to these examples of how overzealous nutrition repletion can paradoxically precipitate deterioration in clinical status.
This article has been cited by other articles:
|
|
 |
|
  C. Nyirenda, I. Zulu, E. K Kabagambe, S. Bagchi, D. Potter, C. Bosire, Z. Krishnasami, and D. C Heimburger Acute hypophosphataemia and hypokalaemia in a patient starting antiretroviral therapy in Zambia--a new context for refeeding syndrome? BMJ Case Reports, April 2, 2009; 2009(apr01_2): bcr0720080469 - bcr0720080469. [Abstract] [Full Text]
|
|
|
|
 |
|
 S. J. Miller Death Resulting From Overzealous Total Parenteral Nutrition: The Refeeding Syndrome Revisited Nutr Clin Pract, April 1, 2008; 23(2): 166 - 171. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Developed in Collaboration With the European Heart, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al. ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death) J. Am. Coll. Cardiol., September 5, 2006; 48(5): e247 - e346. [Full Text] [PDF]
|
|
|
|
 |
|
 Writing Committee Members, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al. ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: A report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death) Developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society Europace, September 1, 2006; 8(9): 746 - 837. [Full Text] [PDF]
|
|
|
|
|
|
J. A. Palesty and S. J. Dudrick The Goldilocks Paradigm of Starvation and Refeeding Nutr Clin Pract, April 1, 2006; 21(2): 147 - 154. [Full Text] [PDF]
|
|
|
|
|
|
J. M. Hasse Nutr Clin Pract, April 1, 2006; 21(2): vii - vii. [Full Text] [PDF]
|
|
|
|
 |
|
 M. D. Kraft, I. F. Btaiche, G. S. Sacks, and K. A. Kudsk Treatment of electrolyte disorders in adult patients in the intensive care unit Am. J. Health Syst. Pharm., August 15, 2005; 62(16): 1663 - 1682. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Heer, C. Mika, I. Grzella, C. Drummer, and B. Herpertz-Dahlmann Changes in Bone Turnover in Patients with Anorexia Nervosa during Eleven Weeks of Inpatient Dietary Treatment Clin. Chem., May 1, 2002; 48(5): 754 - 760. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L Håglin Hypophosphataemia in anorexia nervosa Postgrad. Med. J., May 1, 2001; 77(907): 305 - 311. [Full Text]
|
|
|
|
 |
|
 B. R. Bistrian Dietary Treatment in Secondary Wasting and Cachexia J. Nutr., January 1, 1999; 129(1): 290S - 290S. [Full Text] [PDF]
|
|
|
|
 |
|
 J. F. Buell, A. C. Berger, J. S. Plotkin, P. C. Kuo, and L. B. Johnson The Clinical Implications of Hypophosphatemia Following Major Hepatic Resection or Cryosurgery Arch Surg, July 1, 1998; 133(7): 757 - 761. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. R. Duerksen and N. Papineau Electrolyte Abnormalities in Patients With Chronic Renal Failure Receiving Parenteral Nutrition JPEN J Parenter Enteral Nutr, March 1, 1998; 22(2): 102 - 104. [Abstract] [PDF]
|
|
|
|
|
|
P. E. Marik and M. K. Bedigian Refeeding Hypophosphatemia in Critically Ill Patients in an Intensive Care Unit: A Prospective Study Arch Surg, October 1, 1996; 131(10): 1043 - 1047. [Abstract] [PDF]
|
|
|
|
|
|
T. Maier-Dobersberger and H. Lochs Enteral Supplementation of Phosphate Does Not Prevent Hypophosphatemia During Refeeding of Cachectic Patients JPEN J Parenter Enteral Nutr, March 1, 1994; 18(2): 182 - 184. [Abstract] [PDF]
|
|
|
|
|
|
T. Havala and E. Shronts Managing the Complications Associated With Refeeding Nutr Clin Pract, February 1, 1990; 5(1): 23 - 29. [PDF]
|
|
|
|
 |
|
 D. D. Schocken, J. D. Holloway, and P. S. Powers Weight Loss and the Heart: Effects of Anorexia Nervosa and Starvation Arch Intern Med, April 1, 1989; 149(4): 877 - 881. [Abstract] [PDF]
|
|
|
|
|
|
D. A. Powers, R. O. Brown, G. S.M. Cowan JR, R. W. Luther, D. A. Sutherland, and P. G. Drexler Nutritional Support Team vs Nonteam Management of Enteral Nutritional Support in a Veterans Administration Medical Center Teaching Hospital JPEN J Parenter Enteral Nutr, November 1, 1986; 10(6): 635 - 638. [Abstract] [PDF]
|
|
|
|
|
|
S. Kimura, O. Nose, Y. Seino, T. Harada, S. Kanaya, H. Yabuuchi, T. Itakura, Y. Takagi, and A. Okada Effects of Alternate and Simultaneous Administrations of Calcium and Phosphorus on Calcium Metabolism in Children Receiving Total Parenteral Nutrition JPEN J Parenter Enteral Nutr, September 1, 1986; 10(5): 513 - 516. [Abstract] [PDF]
|
|
|
|
|
|
P. Knight, D. Heer, and G. Abdenour CaxP and Ca/P in the Parenteral Feeding of Preterm Infants JPEN J Parenter Enteral Nutr, March 1, 1983; 7(2): 110 - 114. [Abstract] [PDF]
|
|
|
|
|
|
R. L. Weinsier, J. Bacon, and C.E. Butterworth JR Central Venous Alimentation: A Prospective Study of the Frequency of Metabolic Abnormalities Among Medical and Surgical Patients JPEN J Parenter Enteral Nutr, September 1, 1982; 6(5): 421 - 425. [Abstract] [PDF]
|
|
|
|
 |
|
 L. A. Sunyecz, A. J. Cicci, and J. M. Mirtallo Nutrition Support of the Diabetic Patient Clin-Alert, January 1, 1973; 11(1): 290 - 299. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
