American Journal of Clinical Nutrition, Vol 34, 1861-1867, Copyright © 1981 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Effects of osmolality of liquid nutrient diets on plasma equilibration of water and carbohydrate in Yucatan miniature swine

GL Case, RW Phillips, LD Lewis and B Connolly

Osmolality of a liquid diet was varied from 250 to 700 mOsm/kg by altering the amount of sucrose and corn syrup solids, while maintaining the same level of calories, protein, and electrolytes. The appearance of 3H and 14C in blood plasma were monitored during a 4-h period after pigs voluntarily consumed one of five diets labeled with 3H2O and U-14C- sucrose. Plasma osmolality and sodium and potassium concentrations in plasma did not differ among the diets. Postprandial plasma glucose concentration response to the diets varied both between and within treatments. The rates of radioactive tracer appearance in plasma suggest that water and carbohydrate absorption were accelerated with increasing osmolality of diet up to 700 mOsm/kg.

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