|
|
||||||||
American Journal of Clinical Nutrition, Vol 35, 1023-1032, Copyright © 1982 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
LB Bailey, PA Wagner, GJ Christakis, CG Davis, H Appledorf, PE Araujo, E Dorsey and JS Dinning
The folacin and iron status of 193 adolescents from urban low-income households was evaluated. Red blood cell folacin concentrations were less than 140 ng/ml in 42% of the subjects and 140 to 159 ng/ml in 13%. Of the serum folacin values, 45% were less than 6 ng/ml, and 15% were below 3 ng/ml. Serum folacin levels decreased with increasing age (p less than 0.01) and sexual maturity (p less than 0.05). Transferrin saturation was low (less than 16%) in 12% of the females and 2% of the males. Transferrin saturation levels for females declined as age increased in contrast to an increase over age in males (p less than 0.01). Eleven percent of the females and 3% of the males were classified as anemic (less than 12 g/dl). Mean cell Hb concentration was low (less than 32%) in 24% of the females and 7% of the males. Of all subjects, 17% had low mean cell volumes (less than 81 mum 3). These findings demonstrate folacin and iron status is less than adequate in a significant proportion of this adolescent population group.
This article has been cited by other articles:
![]() |
I. Ifergan, G. Jansen, and Y. G. Assaraf The Reduced Folate Carrier (RFC) Is Cytotoxic to Cells under Conditions of Severe Folate Deprivation: RFC AS A DOUBLE EDGED SWORD IN FOLATE HOMEOSTASIS J. Biol. Chem., July 25, 2008; 283(30): 20687 - 20695. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. N. AMES Micronutrient Deficiencies: A Major Cause of DNA Damage Ann. N.Y. Acad. Sci., January 1, 1999; 889(1): 87 - 106. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. C. Blount, M. M. Mack, C. M. Wehr, J. T. MacGregor, R. A. Hiatt, G. Wang, S. N. Wickramasinghe, R. B. Everson, and B. N. Ames Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage PNAS, April 1, 1997; 94(7): 3290 - 3295. [Abstract] [Full Text] [PDF] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |