| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
American Journal of Clinical Nutrition, Vol 36, 602-610, Copyright © 1982 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
J Lopes, DM Russell, J Whitwell and KN Jeejeebhoy
Skeletal muscle function was studied in 10 malnourished patients with various gastrointestinal disorders and in 22 normal subjects. The function of the adductor pollicis muscle was assessed by electrical stimulation of the ulnar nerve. The objective parameters of muscle function measured were: 1) Force of contraction expressed as a percentage of the maximal force obtained with electrical stimulation at 10, 20, 30, 50 and 100 Hz. 2) Maximal relaxation rate expressed as percentage force loss/!10 ms. 3) Endurance expressed as percentage force loss/30 s. The force of contraction at 10 Hz was higher in malnourished patients compared with normal subjects, with a mean +/- SEM (n) of 43.0 +/- 4.2% (n = 10) and 28.8 +/- 1.2% (n = 22), respectively, (p less than 0.001). The maximal relaxation rate was slower in patients compared with normals with a mean +/- SEM (n) of 7.2 +/- 0.4% (n = 9) ad 9.6 +/- 0.2% (n = 22), respectively, (p less than 0.001). Muscle endurance testing showed an increased force loss with prolonged tetanic stimulation in patients compared with normals, with a mean +/- SEM (n) of 29.1 +/- 4.0% (n = 7) and 3.5 +/- 0.8% (n = 22), respectively, (p less than 0.001). Four patients were restudied after a 4-wk period of total parenteral nutrition, with a significant improvement in muscle function parameters. Malnutrition results in both increased muscle fatiguability and an altered pattern of muscle contraction and relaxation which are reversible by nutritional supplementation. This technique promises to be valuable in assessing the functional effects of malnutrition and the response to nutritional support.
This article has been cited by other articles:
|
|
 |
|
  G. Gardini Gardenghi, E. Boni, P. Todisco, F. Manara, A. Borghesi, and C. Tantucci Respiratory Function in Patients With Stable Anorexia Nervosa Chest, November 1, 2009; 136(5): 1356 - 1363. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W J Marshall Nutritional assessment: its role in the provision of nutritional support J. Clin. Pathol., October 1, 2008; 61(10): 1083 - 1088. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. R Wolfe The underappreciated role of muscle in health and disease. Am. J. Clinical Nutrition, September 1, 2006; 84(3): 475 - 482. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. M. Dias, C. P. Passaro, V. R. Cagido, M. Einicker-Lamas, J. Lowe, E. M. Negri, V. L. Capelozzi, W. A. Zin, and P. R. M. Rocco Effects of undernutrition on respiratory mechanics and lung parenchyma remodeling J Appl Physiol, November 1, 2004; 97(5): 1888 - 1896. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Matecki, G. Py, K. Lambert, C. Peyreigne, J. Mercier, C. Prefaut, and M. Ramonatxo Effect of Prolonged Undernutrition on Rat Diaphragm Mitochondrial Respiration Am. J. Respir. Cell Mol. Biol., February 1, 2002; 26(2): 239 - 245. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Akner and T. Cederholm Treatment of protein-energy malnutrition in chronic nonmalignant disorders Am. J. Clinical Nutrition, July 1, 2001; 74(1): 6 - 24. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L.-W. Chu, K. S. L. Lam, S. C. F. Tam, W. J. H. C. Hu, S.-L. Hui, A. Chiu, K.-C. Chiu, and P. Ng A Randomized Controlled Trial of Low-Dose Recombinant Human Growth Hormone in the Treatment of Malnourished Elderly Medical Patients J. Clin. Endocrinol. Metab., May 1, 2001; 86(5): 1913 - 1920. [Abstract] [Full Text]
|
|
|
|
 |
|
 Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease . A Statement of the American Thoracic Society and European Respiratory Society Am. J. Respir. Crit. Care Med., April 1, 1999; 159(4): S2 - 40. [Full Text] [PDF]
|
|
|
|
 |
|
 J Norwood, D Short, and N Dakhill Prescribing of nutritional supplements is increasing in general practice BMJ, March 20, 1999; 318(7186): 808 - 808. [Full Text]
|
|
|
|
 |
|
 S. D. Brooks, B. B. Gerstman, K. P. Sucher, and P. J. Kearns The Reliability of Muscle Function Analysis Using Different Methods of Stimulation JPEN J Parenter Enteral Nutr, September 1, 1998; 22(5): 331 - 334. [Abstract] [PDF]
|
|
|
|
|
|
J. Potter, P. Langhorne, and M. Roberts Routine protein energy supplementation in adults: systematic review BMJ, August 22, 1998; 317(7157): 495 - 501. [Abstract] [Full Text]
|
|
|
|
 |
|
 N. Hanchard, M Williamson, R W Caley, and R G Cooper Electrical stimulation of human tibialis anterior: (A) contractile properties are stable over a range of submaximal voltages; (B) high- and low-frequency fatigue are inducible and reliably assessable at submaximal voltages Clinical Rehabilitation, May 1, 1998; 12(5): 413 - 427. [Abstract] [PDF]
|
|
|
|
|
|
P. J. Finn, L. D. Plank, M. A. Clark, A. B. Connolly, and G. L. Hill Assessment of Involuntary Muscle Function in Patients After Critical Injury or Severe Sepsis JPEN J Parenter Enteral Nutr, September 1, 1996; 20(5): 332 - 337. [Abstract] [PDF]
|
|
|
|
|
|
G. L. Hill Jonathan E. Rhoads Lecture. Body Composition Research: Implications for the Practice of Clinical Nutrition JPEN J Parenter Enteral Nutr, May 1, 1992; 16(3): 197 - 218. [PDF]
|
|
|
|
|
|
M. L. Nishio and K. N. Jeejeebhoy Effect of Malnutrition on Aerobic and Anaerobic Performance of Fast- and Slow-Twitch Muscles of Rats JPEN J Parenter Enteral Nutr, May 1, 1992; 16(3): 219 - 225. [Abstract] [PDF]
|
|
|
|
|
|
T. R. Ziegler, L. S. Young, E. Ferrari-Baliviera, R. H. Demling, and D. W. Wilmore Use of Human Growth Hormone Combined with Nutritional Support in a Critical Care Unit JPEN J Parenter Enteral Nutr, November 1, 1990; 14(6): 574 - 581. [Abstract] [PDF]
|
|
|
|
|
|
A. R. Webb, L. A. Newman, M. Taylor, and J. B. Keogh Hand Grip Dynamometry as a Predictor of Postoperative Complications Reappraisal Using Age Standardized Grip Strengths JPEN J Parenter Enteral Nutr, January 1, 1989; 13(1): 30 - 33. [Abstract] [PDF]
|
|
|
|
|
|
K. G. Lundholm and C. Drott Optimal Nutritional Indexes in Cancer Patients JPEN J Parenter Enteral Nutr, September 1, 1987; 11(5_suppl): 135S - 137S. [Abstract] [PDF]
|
|
|
|
|
|
D. R. Hunt, B. J. Rowlands, and D. Johnston Hand Grip Strength--A Simple Prognostic Indicator In Surgical Patients JPEN J Parenter Enteral Nutr, November 1, 1985; 9(6): 701 - 704. [Abstract] [PDF]
|
|
|
|
|
|
D. Mcr. Russell, H. L. Atwood, and K. N. Jeejeebhoy Nitrogen versus Muscle Calcium in the Genesis of Abnormal Muscle Function in Malnutrition JPEN J Parenter Enteral Nutr, July 1, 1985; 9(4): 415 - 421. [PDF]
|
|
|
|
|
|
A. S. Detsky, R. A. Mendelson, J. P. Baker, and K. N. Jeejeebhoy The Choice to Treat All, Some, or No Patients Undergoing Gastrointestinal Surgery with Nutritional Support: A Decision Analysis Approach JPEN J Parenter Enteral Nutr, May 1, 1984; 8(3): 245 - 253. [Abstract] [PDF]
|
|
|
|
|
|
D. S. Mclaren and M. M. Meguid Nutritional Assessment at the Crossroads JPEN J Parenter Enteral Nutr, November 1, 1983; 7(6): 575 - 579. [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
