| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
American Journal of Clinical Nutrition, Vol 37, 1-4, Copyright © 1983 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
A Geliebter, N Torbay, EF Bracco, SA Hashim and TB Van Itallie
The study was designed to determine whether overfeeding rats with a diet containing medium-chain triglyceride (MCT) as the major fat source (45% of calories) would impede the expected gain in weight and body fat as compared to rats overfed with isocaloric amounts of diet containing long-chain triglyceride (LCT). For 6 wk rats were fed either MCT diet or LCT diet twice daily via a gastrostomy tube. MCT-fed rats gained 20% less weight (P less than 0.001) and possessed fat depots weighing 23% less (p less than 0.001) than LCT)-fed rats. Mean adipocyte size was smaller (p less than 0.005) in MCT- than in LCT-fed rats. Weights of carcass protein and water were similar for both groups as were concentrations of serum insulin and levels of physical activity. The decreased deposition of fat in the MCT-fed rats may have resulted from obligatory oxidation of MCT-derived fatty acids in the liver after being transported there via the portal vein, leaving almost no MCT derivatives for incorporation into body fat. MCT may have potential for dietary prevention of human obesity.
This article has been cited by other articles:
|
|
 |
|
  M. Newell-McGloughlin Nutritionally Improved Agricultural Crops Plant Physiology, July 1, 2008; 147(3): 939 - 953. [Full Text] [PDF]
|
|
|
|
 |
|
 M.-P. St-Onge and A. Bosarge Weight-loss diet that includes consumption of medium-chain triacylglycerol oil leads to a greater rate of weight and fat mass loss than does olive oil Am. J. Clinical Nutrition, March 1, 2008; 87(3): 621 - 626. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M.-P. St-Onge, B. Lamarche, J.-F. Mauger, and P. J. H. Jones Consumption of a Functional Oil Rich in Phytosterols and Medium-Chain Triglyceride Oil Improves Plasma Lipid Profiles in Men J. Nutr., June 1, 2003; 133(6): 1815 - 1820. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Han, S. R. Farmer, J. L. Kirkland, B. E. Corkey, R. Yoon, T. Pirtskhalava, Y. Ido, and W. Guo Octanoate Attenuates Adipogenesis in 3T3-L1 Preadipocytes J. Nutr., May 1, 2002; 132(5): 904 - 910. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.-P. St-Onge and P. J. H. Jones Physiological Effects of Medium-Chain Triglycerides: Potential Agents in the Prevention of Obesity J. Nutr., March 1, 2002; 132(3): 329 - 332. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Tsuji, M. Kasai, H. Takeuchi, M. Nakamura, M. Okazaki, and K. Kondo Dietary Medium-Chain Triacylglycerols Suppress Accumulation of Body Fat in a Double-Blind, Controlled Trial in Healthy Men and Women J. Nutr., November 1, 2001; 131(11): 2853 - 2859. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. D White, A. A Papamandjaris, and P. J. Jones Enhanced postprandial energy expenditure with medium-chain fatty acid feeding is attenuated after 14 d in premenopausal women Am. J. Clinical Nutrition, May 1, 1999; 69(5): 883 - 889. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Del Prado, G. Delgado, and S. Villalpando Maternal Lipid Intake During Pregnancy and Lactation Alters Milk Composition and Production and Litter Growth in Rats J. Nutr., March 1, 1997; 127(3): 458 - 462. [Abstract] [Full Text]
|
|
|
|
 |
|
 E. J. Pappert, C. C. Tangney, C. G. Goetz, Z. D. Ling, J. W. Lipton, G. T. Stebbins, and P. M. Carvey Alpha-tocopherol in the ventricular cerebrospinal fluid of Parkinson's disease patients: Dose-response study and correlations with plasma levels Neurology, October 1, 1996; 47(4): 1037 - 1042. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
